Method Development System

Automatic Optimization of Gradient Conditions with AI Algorithm

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Solution for Method Development and Analytical Quality by Design

Improving Efficiency of the Entire Method Development Workflow

Method Scouting

LabSolutions™ MD improves method development efficiency by taking an Analytical Quality by Design (AQbD) approach. This software efficiently develops highly reliable analysis methods by configuring mobile phases, columns, and other parameters using an analysis function that automatically generates analysis schedules with the experimental design method and a data analysis function that plots a design space and predicted chromatogram.
LabSolutions MD supports not only LC detectors such as "UV detector" and "PDA detector," but also the "single quadrupole LC/MS detector." By utilizing the high qualitative capabilities of the LC/MS detector, it aids in the development of more reliable analytical methods through accurate compound identification. It is also compatible with our latest LC/MS detector, LCMS-2050.

LabSolutions MD

 

Workflow

Features

  • Reduce the Number of Data Points Using Experimental Design
    Optimization
    Box-Behnken design and central composite design can shorten analysis times because they require fewer data points than full factorial design.

    Method Scouting Solution doesn’t support creating experimental design.
  • Automatic Optimization of Gradient Conditions
    Automatic Optimization of Gradient Conditions
    LabSolutions MD has a unique AI algorithm for automatic optimization of gradient conditions. By setting resolution criteria, it automatically searchs for the gradient conditions that meet the criteria.
  • Save Labor by Switching between Mobile Phases and Columns Automatically
    Automated Column and Mobile Phases Switching
    In addition to automatically switching between multiple mobile phases and multiple columns, mobile phase blending functionality can also save labor by automating mobile phase preparation. LabSolutions MD is compatible with Nexera series and i-Series systems.

    LabSolutions MD doesn’t support SFC system.
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Videos

  • Method development and Identification of Triacylglycerols species with SFC

    • Liquid Chromatography
    • SFC

    Analyzing Triacylglycerols (TAGs) is essential to evaluate the quality and functionality of oils and fats. Chromatographic separation by typical methods that include GC and HPLC might be challenging due to a large number of TAGs species. Supercritical Fluid Chromatography (SFC) is one chromatography method that uses supercritical fluid (i.e. supercritical carbon dioxide) as a mobile phase. Here, we introduce the workflow of method scouting of SFC using Method Scouting Solutions and how to establish the optimized analytical method for TAGs species in natural oils and fats.

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